Who We Are. Our Mission.
Pathway Genomics’ mission is to ensure that people in need receive genetic testing regardless of their economic or insurance status. Offering BRCATrueTM, the industry’s best BRCA genetic test, and making it accessible to a wide range of people is a vital objective in this mission.
To enhance the accessibility of BRCATrue, we have developed the BRCA One for OneTM program – for every qualified BRCATrue test ordered, one test is donated to a person in need through patient advocacy organizations, up to $10 million of free testing.*
HOW IT WORKS
What are BRCA1 and BRCA2?
DNA changes in the BRCA1 and BRCA2 genes can lead to significantly increased lifetime risks for breast and ovarian cancer. Additionally, mutations in BRCA1 and BRCA2 can lead to a condition known as hereditary breast and ovarian cancer syndrome, also known as HBOC.
Hereditary Breast and Ovarian Cancer
DNA changes, also called mutations, in the BRCA1 and BRCA2 genes can lead to significantly increased lifetime risks for breast and ovarian cancer. Mutations in BRCA1 and BRCA2 lead to a condition known as hereditary breast and ovarian cancer syndrome, or HBOC, which accounts for 5 to 7 percent of breast cancer cases1 and 8 to 13 percent of epithelial ovarian cancer cases.2 However, BRCA1 and BRCA2 mutations account for up to 80 percent of breast and ovarian cancer in families with multiple cases of either disease.3, 4, 5
BRCA1/2 and Ethnicity
Large population studies6, 7 of breast cancer survivors under the age of 65 revealed strong ethnic differences in the prevalence of pathogenic mutations in the BRCA1 and BRCA2 gene. See the table below for examples:
*The BRCA One for One program only applies for BRCATrue tests sold that are covered by insurance. The program is limited to up to $40,000 in tests per month and up to $10 million in tests in the aggregate.